Muscle cramping
I haven't been diagnosed with MG but my doctors and I are believe it is likely causing my symptoms, notably double vision and extreme muscle fatigue that varies throughout the day. AcHR and MuSK were both negative but I asked for some additional tests before we rule out MG.
My main question revolves around muscle cramping. I'm addition to profound muscle weakness at times, I have intense muscle cramping (mostly in the legs but also sometimes in the arms). It feels like my muscles are trying to contort in an unnatural way and I am unable to relax them. Afterwards they will be so sore and it feels like I did a really intense workout. If I try to use that muscle after it will burn and become numb and weak within minutes.
My muscles ache reflexes are also very sensitive. A gentle touch can cause then to spasm.
Does anyone with MG experience this? Or should I be considering different diseases?
Wakes me up every couple of nights
The day I was diagnosed at the Neurologist's rooms, I had a physical examination and a nerve conduction test, with the fibre needle included. The test on my legs were evident that there was very little communication between the nerve and the muscle, plus the muscles take long to recover. I was prescribed mestinon, and afterwards a blood test was done. The blood test was normal. So it was evident I was really deathly ill, with endless dreadful fatigue and pain , 24/7 legs cramping, hair falling out and loosing so much weight, falling too many times and breaking my wrist.
Let me just add a crisis can include these symptoms too with the deathly fatigue, pain and cramping. MG is a horrible disease. I take Mestinon 60mg x 4, epitec 50mg for the sensitive nerves and cramping and dulta 60mgs that assists with the constant pain I deal with daily. It is hard, very hard to walk. Feeling a new normal is great. It has taken long to recover. I do not take cortisone or am immunosuppressive.
It will be what it is. When I was diagnosed it was starting at the back of the base of my head, very heavy and sore at night. My ears still vibrate. I had at the time swallowing and a tight tongue. The ears still vibrate, the throat can be a little difficult.
I have to be grateful 🙏🏻 and happy everyday, I can walk. With lots of effort at times. I was on deaths door had I not been diagnosed and taken seriously I would have died or been worse off in 2022.I never had muscle cramps until I was diagnosed with MG. A friend told me to take a couple of spoonfuls of dill pickle juice. It worked within a couple of minutes. Also, vinegar would work too.
I used to have cramp every night when I was taking p to pyradostimine for MG but the cramp stopped when I stopped taking the pyradostimine (mestonin).
Pyridostigmine floods your muscles with acetylcholine by suppressing the mechanism that gets rid of it. This is very good in the beginning because you need all the acetylcholine you can get to counter the attack of antibodies. But as your other meds kick in, the anti-body attack lessens, and you don't use all that acetylcholine. Too much acetylcholine buildup will cause muscle cramps.
