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Azathioprine (Imuran)

Hello, I am newly diagnosed as of November '22. I am responding well to Pyridostigmine, with speech and swallowing problems greatly reduced. Now my neurologist wants me to take Azathioprine (Imuran). I asked him "what additional benefit" the new drug would have and his response was.... "Azathioprine is part of the treatment protocol." We went back and fourth several times and he never answered me. I am reluctant to take more drugs when I am doing well and was wondering if anyone else in the group is on both drugs and what your experience has been.

  1. Hi there, welcome to our MG community. Here is an article outlining the treatment: https://myasthenia-gravis.com/living/azathioprine and I also wanted to share a few other forums/stories where community members have shared their experience with it: https://myasthenia-gravis.com/forums/your-azathioprine-imuran-side-effect-experience, https://myasthenia-gravis.com/stories/new-life I hope you find this information helpful! Best wishes, Kaitlyn (Team Member)

    1. Thanks so much! Reading the first article I see that Azathioprine has a strong interaction with a drug I take called Allopurinol (for kidney stones). I relayed this to the neurologist and we agreed not to start on the Azathioprine. Thanks to all who responded to my note.

  2. Soon after my diagnosis I was put on imuran along with Mestinon I was told that drug can take as much as 6 to 8 months or even a year to work in your system I have now taken imuran over one year with no results that I am aware of very difficult to tell as I have had Vyvgart and IV I G my NE is taking me off and putting me on cell cep which I understand can take a few months of transition

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