Not sure this is related, but I cramp in my fingers and toes. Occasionally a calf cramp and mid back. I'm gMG seropositive. I've dosed 5 60mg Mestinon a day. Given the nature of Mestinon in essence increasing the acetylcholine present in the neuro gap I mentioned this to my neurologist and he backed me down to 4 a day. Seems to have worked (much less events), but this dosing of medication is very delicate and like MG very individual based; check with your doctor. Just some food for thought.