I am 71 and have only been dealing with MG for a little over a year. I have always been very active, gym 5 days a week and cardio at home on my off days. I have slowly had to dial it back and make changes in frequency in order to have some recovery time. I recently changed to an every other day gym routine and rather than hike up the steep trail I now take the flat one but the same distance, running is now out of the question. I will continue to adjust but hopefully be able to improve rather than regress, but it is what it is.