Dramatic changes in MG symptoms for the better
I was diagnosed in December 2023 with GM at the time it was ocular with a continuous migrain rtype headache using Pyridostigmine and propranolol royally eliminated that . I then had pain ams muscle weakness in neck arms and legs ..it was like carrying lead weights around i struggled to get up from a chair or from my bed
. I have ostiparosis in both knees and on 12th May I had a cortisone injection into one knee ..it was like a miracle..all my muscle weakness and pain has totally gone away ..I'm due a jab in thr other knee on 9th June . My tests for MG all came back negative ..so have I really got it , is this a temporary improvement .. I am waiting for an appointment with my nuro surgeon but the hospital is behind with their appointments so still waiting ..but since I last saw him my symptoms have dramatically changed twice..a yway I'm making the most of feeling so well and am hoping it lasts .
Propranolol is known to potentially worsen MG symptoms. Did you experience this when you were taking it? - Jodi, Team Member
Diagnosed with OMG several months ago. Pyridostigmine has reduced double vision to occasional and very minor. I do have migraine type headaches and some mild vertigo. Neurologist prescribed Propranolol---should I be concerned about taking it? Only been on Propranolol for about a week and not much relief yet. We are not allowed to provide medical advice. I can provide you with these studies about Propranolol and Myasthenia gravis: https://www.ncbi.nlm.nih.gov/pmc/articles/PMC7457047/, https://onlinelibrary.wiley.com/doi/10.1111/ene.14996, https://www.nejm.org/doi/10.1056/NEJMc1701027, https://www.medlink.com/articles/drug-induced-myasthenic-syndromes, https://journals.sagepub.com/doi/10.1177/19418744231206256. Propranolol is a beta-blocker that is generally recommended to avoid with MG, based on the experience of some: https://myasthenia-gravis.com/clinical/drugs-vaccines-to-avoid. But sometimes drugs that are advised against with MG are needed, which, in this case, I like how this document labels drugs by risk level for MG individuals: https://nebula.wsimg.com/903ebe2c701eb4e72e3211dc9fb9064e?AccessKeyId=7F50FBE19A111D19DDAC&disposition=0&alloworigin=1. Keep in mind that MG is very unique. Hence, it is impossible to predict any reaction to a drug. - Jodi, Team Member
Hi
, It sounds like the cortisone injection was a big relief. I hope it goes well on June 9th - please keep us posted! We encourage you to share all these notes and changes in symptoms when you have your appointment. It can be really frustrating when symptoms change and are unpredictable, but we have heard from others here that keeping a log of those symptoms and discussing it during the appointment can be really helpful. I wanted to share an article about seronegative MG: https://myasthenia-gravis.com/seronegative This is when someone has MG but their blood work is negative. Hopefully you find the answers you deserve when you are able to get in for your appointment. We will be thinking of you! Best, Lauren (Myasthenia-Gravis.com Team)
