caret icon Back to all discussions

Getting a handle on MG (or trying)

I have been having fairly frequent flairs, due to stress, summer heat, and just too much exertion. And I have to admit I have gotten a little depressed about that. I have been on a 10 mg daily dose of Prednisone and 10 - 60 mg quick release tablets of Pyridostigmine, spread equally throughout the waking hours. And I still was getting times when I could not shave, or brush my teeth due to twitching and muscle weakness. I was having difficulty lifting my water bottle to my mouth to drink sometimes.

My latest visit with my neurologist. He considers my MG not under good control. He wants to increase my Predinisone, going to 20 mg for a week, then 30, then 40, until I hit 50 by week 4 in an effort to get it under control. His idea is if increasing it works to bring the MG under better control, I should then cut down on the quantity of quick release Pyridostigmine. Managed well enough, and reducing the Pyridostigmine to an almost "as needed" level rather than needing 10 pills per day just to keep the basic symptoms at bay. If I can't get it under control with this method then he says I will likely need to resort to IVIG treatments once a month.

Then if that works, he will then try to reduce the Prednisone down from the new level of 50 mg daily back down as close as we can get to 10 or 20 mg without having to take as many of the quick release Pyridostigmine to cover the symptoms.

I am still in the first week of increasing the Prednisone from 10 to 20 mg. I am thinking it is helping. I am wondering if anyone else has been on a similar treatment plan. Should I wait until I hit the 50 mg dose of Prednisone at week 4 before I start trying to reduce the daily quantity of Pyridostigmine? Or if I am already feeling an improvement can I drop a tablet and see what happens?

It would be lovely not to need 10 pills daily of the Pyridostigmine

opinions/thoughts/experiences?

    Please read our rules before posting.