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New member, I suspect MG - please confirm which bloodtest I need?

Dear all

I am a new member here. I have had MG symptoms for well over 14 years now but its never been formally diagnosed.

It started all at the same time where the facial palsy happened on the left of my face with a droopy eyelid and droopy left mouth together with "tearing" on the same side. The doctor diagnosed this as facial palsy and sent me to a neurologist for further tests.

Then my voice became very hoarse and I have a constant lump in the throat which never goes away - I always find it hard speaking either publicly or for long periods. My tongue also seems to be thust against the rear of my front teeth leaving dents/dimples in the tongue - it is constantly tense and I feel it larger than it usually is.

The palsy was diagnosed as the cranial nerve and I was put on a set of powerful steroids for 1 week which definitely improved the palsy symptoms and the tearing but did not cure it.

Then I was sent to ENT to look at my vocal cords and everything seemed in order so I am now having vocal therapy which doesn't change anything, the underlying symptoms are constantly there with the lump in the throat and hoarseness and my tongue thrust.

I have been clutching at straws trying to understand what condition I have and even asked for a set of thyroid tests goven its proximity to the vocal cords but the thyroid is functioning normal. I also feel mostly depressed but before this I was a very positive person.

Having come across MG over the weekend, I am keen to ask my GP for a new set of blood tests on Monday. Could someone kindly let me know what I need to request and what ranges the blood values need to come back at please? I am literally tearing my hair out especially with my voice as I cannot function at work and people are yawning when I talk which is very disheartening when I am trying to be impactful. Thank you!

  1. Thank you for your reply David75. I have a blood test booked in on the 14th so will report back then.

    In the meantime, is there anything I can do to relieve the pressure on my voice and speak without the voice breaking up or sounded weak as I have an interview this week and need to be on top form. Many thanks

    1. In the early stages, years ago, a pyridostigmine really helped my voice. Now it's just petty much always weak. Sorry. Maybe someone else can help???????

  2. Hi Codey. If you have MG, your blood will contain an antibody that shouldn't be there. It will usually be anti-acetylcholine antibody, but it could be anti-MUSK antibody. It's the same test for either. Just ask for the myasthenia gravis blood test.
    The value doesn't matter. Any level of antibody indicates MG. It's not unusual to have to encourage a doctor to test for it. Most have no experience with MG. The test is a simple blood draw and the results are back within a few days. Good luck.

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