caret icon Back to all discussions

Leg and Foot Cramping and Pain

Many individuals with Myasthenia gravis report having intensive leg/foot cramps and pain, most specifying this occurring predominately at night.

Do you experience leg pain? Describe the sensation, and if you note the treatments you are on, that would be great. Pyridostigmine is associated with cramping. But from personal experience, I believed this to cause my leg pain until I stopped mestinon, which has continued. I am sure many of you are the same way.

I look forward to seeing any trends we may note with our community here and our lower body cramps experiences.

Feel free to share any advice you have found for relief 😀
- Jodi, Team Member

  1. I have experienced cramps at night for many years due to chronic kidney disease, but it's much worse now with the MG and Neuropathy. I don't know which aspect of my health is the culprit but I do know that pickles and pickle juice do help quite a bit.

  2. YES, both thighs....weakness and pain

  3. I was told by several doctors and independent research that MG affects motor synapses only not sensory impulses like your foot or leg. I have had both foot and lower leg problems in the last year. Have had infections in my leg and in another post talked about my leg vein procedures. Went fine, but now the bottom/top of my foot and ankle are swelling up and giving me pain and balance troubles. Problem with right foot ROM and ankle stiffness. will return to my vein specialist in about two weeks for follow up and results of my U/S where vein surgery occurred.

  4. It is easy to blame MG for so many health problems and sometimes there is no relation to the new symptoms. I developed plantar fasciitis in my left foot about 5 months ago. I immediately purchased some orthopedic shoes and now my left foot is so much better ,however, I have developed it in my right foot now. Is weakened muscle strength part of why I am having this problem? I will probably never know.

    1. Thank you, I will certainly speak with my GP, but will be lost if he says not to take them as I get really bad vibrations, cramps and restless legs without them.

Please read our rules before posting.