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Leg and Foot Cramping and Pain

Many individuals with Myasthenia gravis report having intensive leg/foot cramps and pain, most specifying this occurring predominately at night.

Do you experience leg pain? Describe the sensation, and if you note the treatments you are on, that would be great. Pyridostigmine is associated with cramping. But from personal experience, I believed this to cause my leg pain until I stopped mestinon, which has continued. I am sure many of you are the same way.

I look forward to seeing any trends we may note with our community here and our lower body cramps experiences.

Feel free to share any advice you have found for relief 😀
- Jodi, Team Member


  1. I get leg "cramps" That feel like my lower leg from the knee down Is made of clay. If I try to bring my toes towards my head, they will start going on their own and end with the Charlie Horse! Works in the other direction also, as it seems to be affecting everything from the knee down!
    My best method of dealing with this is to walk a little bit and then get into my hot tub. it is not unusual for me to be in the hot tub at 5AM!

    1. I had bad foot cramps and painful shinsplints. Doctor reduced Mestinon

      1. Yes.

        1. Knees

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