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Muscle cramping

I haven't been diagnosed with MG but my doctors and I are believe it is likely causing my symptoms, notably double vision and extreme muscle fatigue that varies throughout the day. AcHR and MuSK were both negative but I asked for some additional tests before we rule out MG.

My main question revolves around muscle cramping. I'm addition to profound muscle weakness at times, I have intense muscle cramping (mostly in the legs but also sometimes in the arms). It feels like my muscles are trying to contort in an unnatural way and I am unable to relax them. Afterwards they will be so sore and it feels like I did a really intense workout. If I try to use that muscle after it will burn and become numb and weak within minutes.

My muscles ache reflexes are also very sensitive. A gentle touch can cause then to spasm.

Does anyone with MG experience this? Or should I be considering different diseases?

  1. Two of my fingers on my left hand curl but it doesn't hurt. I use my right hand to straighten them.

    1. Yes

      1. So bad that I can’t use my hands! Switched from azathioprine 3 weeks ago to CellCept. Cutting back on the mestinon as per MD.

        1. Has anyone tried DMSO? What were the results?

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