NEW APPROVED MG TREATMENT for Gmg - Vyvgart Hytrulo
Super exciting!! The FDA has just approved Argenx’s subcutaneous injection (given in the fatty tissue just under the skin) formulation of efgartigimod, called Vyvgart Hytrulo (efgartigimod alfa and hyaluronidase-qvfc) to treat adults with generalized myasthenia gravis.
Efgartigimod alfa is the active agent in Vyvgart and a recombinant human hyaluronidase PH20 enzyme. That enzyme is crucial in the under-the-skin injection delivery, which takes only *90 SECONDS* to be administered. Into-the-vein or intravenous therapy takes about one hour.
Who is interested in this new treatment options? What are your thoughts?
- Jodi, Team Member
My husband has been recently diagnosed with MG. His neuromuscular specialist recommended Vyvgart. The Vyvgart folks reach out to you to talk you through what's going to happen with the infusions, side effects, etc. The nurse I talked to was amazing and answered a lot of questions on MG. If authorization is approved, then they have an insurance person work with you for payment, etc. And they send out a kit with information and log book for you to use. We were excited that this was the answer, but insurance declined even with the neurologist calling and talking to the insurance folks. Traditional route of prednisone and cellcept first and if adverse reactions then reapply for authorization. I can tell you what the co-pay with medicare was for 4 infusions - one a week - $3,065. We are just starting him on the pred/cept this week, but the neurologist has applied for authorization for IVIG infusions since the pyrostygmine is having a limited effect.
Good luck to anyone who has a chance to try this. Please keep everyone informed as to the results.
I can imagine the frustrations you both must have felt. Our community members can definitely relate. I included an article on managing healthcare expenses, just in case you were interested in any information that may be helpful at off setting costs - https://myasthenia-gravis.com/resources-cost. Please know our community is here for you both anytime. Kindly, Jessica, Team Member
I’m waiting to get in and start with a new neurologist. Appointment is late September. Meanwhile I’m watching new symptoms develop as I become more exhausted just dealing with a day in an assisted living place. Would I try this drug? Hell yeah if the neuro approves it! I’m sure it will be beyond expensive, but hopefully Medicare will approve. That will help some as will the prescription insurance!
Best and love to all
Sue
