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PLEX or IVIG Complications?

Have you had complications or issues arise during or after a PLEX (plasma exchange/plasmapheresis) or IVIG (intravenous immunoglobulin injection) treatment?

https://myasthenia-gravis.com/treatment

  1. Jazmin Clayton Let's see, I've had several adverse effects after PLEX treatments.
    1)osmotic diuresis (increased urination) & osmotic diarrhea from the albumin replacement fluid.
    2) hypotension (low blood pressure) despite ml:ml fluid replacement.
    3) low potassium & magnesium due to #2 and plasma removal
    4) depleted fibrinogen (needed for blood clotting
    5) fall with excessive bleeding due to low blood pressure & decreased fibrinogen.
    If PLEX wasn't the only treatment that temporarily decreases my symptoms, I wouldn't do it every 3 weeks.
    I've had no problems with IvIG which I get twice a month.

    1. This is such valuable information; we are very thankful for you passing it along. Others can always benefit from the knowledge of what to possibly expect.

      -Jodi, Team Member

  2. When I get IVIG injections I typically get horrible migraines. Unless I go to the ER due to the pain, I normally cry and moan in agony. Almost immediately after the treatment my body aches. Does anyone experience that? - Jazmin (MG team member)

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