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Toll Prednisone Took on Your Body

What impact did Prednisone have on your body? What symptoms did you experience while on the steroid?

How was your experience weaning off the medication? Have you struggled to do so without adverse reactions? - Jodi, Team Member

  1. My pulse rate went down to 52. Became very lethargic and gaspy. Same reactiion with Mestidone. Now on SCIg. Was on IVIg for 60 weeks.

  2. Osteoporosis after 4 years
    Weight gain = obese (originally thin and fit)
    Varicose veins
    Mood changes
    Thinning skin, bruising and bumps inc acne
    Round face
    Hunch back
    Pot belly
    Gastric upsets
    Insomnia
    Constant hunger



    1. Cazzie has it nailed here, except that she left out diabetes. The side effects of prednisone are terrible. The goal should be to reduce the dosage, over time, as far as possible without falling off the MG cliff. It took me two years to get down to 5 MG daily, relying on azathioprine to keep me stable. I don't see any short-term side effects at that level. There is new research that found a 3.6 MG daily dose was essentially safe. That is to say, it resulted in no observable bad effects out to seven years, the limit of the study. The side-effect curve starts there and goes up sharply as the dosage increases.

  3. Anxiety, irritable, insomnia, manic type symptoms. I was 30 mg for 6 months. My doctor reduced it to 20mg 3 months ago. Said, it would take a year to zero mg. Researching that was extreme. I am managing my reduction, and 15 mg eight weeks.

  4. I was on a high dose of prednisone for Polymyaglia Rheumatica. My blood sugars went completely out of control. I was over 700 for a couple days. In ICU for 4 days. The. High blood sugar caused me to be nearly blind as well as physically ill.

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